Middletown is the oldest town in Dauphin County; laid out in 1755 by George Fisher, Quaker. It was an important port at the junction of the Pennsylvania and Union Canals in the 19th century. It was the site of early flour, lumber, and iron industries.

• Penn State Harrisburg's Capital Campus
• Middletown and Hummelstown Railroad
• Elks Theatre
• The Middletown Area Arts Collective (MAAC)
• Arts on Union
• Middletown Public Library & the Middletown Historical Society Museum
• Harrisburg International Airport
• Middletown Centre Square Walking Tour (5.4 mb - pdf)
• Middletown Downtown Walking Tour (5.2 mb - pdf)
• Historic Homes of Middletown
• Swatara Creek and Susquehanna River
• Union Street Blues